By I Barry Holland, Susan P. C. Cole, Karl Kuchler, Christopher F. Higgins
ABC Proteins is an in-depth, updated research of all that's recognized concerning the topic so far. It discusses and compares evolution, biology and mechanism of motion of all identified ABC proteins, together with the 1st structural reviews in addition to medical implications. it is going to be precious to an individual attempting to remain abreast of the most recent findings. This publication is bound to develop into a vintage and should frequently be updated.
- Phylogeny and Evoloution of ABC Transporters
- Fundamental facets of the Mechanism of motion of ABC Transporters
- Prokaryote ABC Transporters
- Non-Mammalian Transporters
- Multidrug Transporters
- ABC Transporters, Physiological Roles and Human Disease
- Full colour throughout
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Additional info for ABC Proteins: From Bacteria to Man
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Chem. 271, 24321–24324. PHYLOGENETIC AND FUNCTIONAL CLASSIFICATION OF ABC SYSTEMS Jekabsons, W. and Schuster, W. (1995) orf250 encodes a second subunit of an ABC-type heme transporter in Oenothera mitochondria. Mol. Gen. Genet. 246, 166–173. M. R. (1987) Cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium. J. Bacteriol. 169, 3189–3198. , Drobnik, W. and Schmitz, G. (2000) Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7). Biochem. Biophys.
Melanogaster but none in S. cerevisiae. Six of the A. thaliana proteins have an IM-ABC type organization. The DRI family involved in drug resistance, and bacteriocin and lantibiotic immunity This family is composed of systems having the same global organization as those of the DRA family. 1). No significant similarity could be detected between IM proteins of these two families. DRI family systems are found in prokaryotes and some of these are involved in antibiotic resistance and in bacteriocin and lantibiotic immunity.